Thomas Fleming Selected Research

Anserine

7/2020	A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice.
9/2018	Protective Actions of Anserine Under Diabetic Conditions.
1/2018	Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal.

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Thomas Fleming Research Topics

Disease

17	Type 2 Diabetes Mellitus (MODY) 01/2022 - 07/2012
14	Diabetes Complications 01/2022 - 10/2015
12	Hyperglycemia 01/2022 - 01/2015
10	Diabetic Neuropathies (Diabetic Neuropathy) 12/2021 - 06/2012
9	Diabetic Nephropathies (Diabetic Nephropathy) 07/2020 - 11/2015
8	Insulin Resistance 01/2022 - 10/2016
6	Pain (Aches) 01/2021 - 06/2012
6	Inflammation (Inflammations) 01/2021 - 01/2015
6	Obesity 01/2021 - 11/2013
6	Diabetes Mellitus 07/2020 - 01/2017
6	Neoplasms (Cancer) 01/2020 - 09/2010
5	Hyperalgesia 01/2022 - 06/2012
5	Septic Shock (Toxic Shock Syndrome) 01/2019 - 12/2014
4	Peripheral Nervous System Diseases (PNS Diseases) 01/2022 - 11/2013
4	Neuralgia (Stump Neuralgia) 01/2021 - 12/2018
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2019 - 01/2018
3	Fibrosis (Cirrhosis) 01/2022 - 10/2017
3	Albuminuria 01/2020 - 06/2017
3	Sepsis (Septicemia) 01/2019 - 01/2016
3	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2018 - 10/2014
2	Polyneuropathies (Polyneuropathy) 01/2021 - 01/2017
2	Hypoglycemia (Reactive Hypoglycemia) 12/2020 - 01/2019
2	Atherosclerosis 05/2019 - 01/2016
2	Heart Failure 01/2019 - 04/2004
2	Hypersensitivity (Allergy) 01/2019 - 01/2013
2	Ganglion Cysts (Ganglion) 01/2019 - 01/2016
2	Squamous Cell Carcinoma of Head and Neck 01/2017 - 12/2015
2	Stroke (Strokes) 01/2016 - 01/2015
1	Hip Fractures (Intertrochanteric Fractures) 03/2022
1	Liver Diseases (Liver Disease) 01/2022
1	Cardiomegaly (Heart Hypertrophy) 01/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022
1	Starvation 01/2022
1	Demyelinating Diseases (Demyelinating Disease) 12/2021
1	Acute Promyelocytic Leukemia 01/2021
1	Acne Vulgaris 01/2021
1	Disease Progression 01/2021
1	Iron Overload 01/2021
1	Neuroblastoma 01/2021

Drug/Important Bio-Agent (IBA)

24	Pyruvaldehyde (Methylglyoxal)IBA 01/2022 - 11/2009
22	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2009
10	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2014
8	EnzymesIBA 01/2022 - 01/2013
7	Proteins (Proteins, Gene)FDA Link 12/2021 - 01/2017
6	Advanced Glycation End ProductsIBA 01/2022 - 01/2017
5	LipidsIBA 01/2022 - 10/2015
5	NAD (NADH)IBA 01/2020 - 11/2013
4	CytokinesIBA 01/2021 - 01/2015
4	Retinaldehyde (Retinal)IBA 01/2021 - 01/2016
4	Streptozocin (Streptozotocin)FDA Link 01/2019 - 01/2016
3	AntioxidantsIBA 01/2022 - 12/2012
3	Blood Glucose (Blood Sugar)IBA 12/2020 - 09/2018
3	CarnosineIBA 07/2020 - 01/2018
3	AnserineIBA 07/2020 - 01/2018
3	Oxygen (Dioxygen)IBA 04/2019 - 11/2015
3	C-Reactive ProteinIBA 01/2018 - 12/2014
3	LigandsIBA 01/2018 - 01/2015
3	Insulin (Novolin)FDA Link 01/2018 - 10/2016
3	Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA 06/2017 - 10/2016
2	imidazoloneIBA 01/2022 - 01/2019
2	CarbohydratesIBA 01/2022 - 01/2017
2	N 30IBA 01/2022 - 12/2014
2	AlbuminsIBA 01/2022 - 01/2017
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 02/2021 - 01/2021
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2021 - 12/2015
2	Neuroprotective AgentsIBA 01/2021 - 01/2016
2	Peptides (Polypeptides)IBA 01/2021 - 01/2017
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021 - 01/2019
2	LDL CholesterolIBA 05/2019 - 10/2016
2	oxidized low density lipoproteinIBA 05/2019 - 07/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 01/2018
2	aminoacyl-histidine dipeptidaseIBA 12/2017 - 11/2015
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2017 - 11/2015
2	ProcalcitoninIBA 02/2017 - 12/2014
2	Receptor for Advanced Glycation End ProductsIBA 01/2016 - 01/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2015 - 12/2014
1	CreatinineIBA 01/2022
1	Histones (Histone)IBA 01/2022
1	Ketone BodiesIBA 01/2022
1	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 01/2022
1	GlucokinaseIBA 01/2022
1	Aldehyde DehydrogenaseIBA 01/2022
1	Urokinase Plasminogen Activator ReceptorsIBA 01/2022
1	acetolIBA 01/2022
1	Messenger RNA (mRNA)IBA 12/2021
1	Myelin P0 Protein (Myelin Protein Zero)IBA 12/2021
1	Vitamin A (Retinol)FDA LinkGeneric 01/2021
1	AcidsIBA 01/2021
1	MagnesiumIBA 01/2021
1	Opioid Analgesics (Opioids)IBA 01/2021
1	IronIBA 01/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021
1	PhosphoenolpyruvateIBA 12/2020

Therapy/Procedure

6	Therapeutics 01/2021 - 04/2004
2	Injections 01/2019 - 09/2018
2	Glycemic Control 01/2016 - 07/2015
1	Fracture Fixation 03/2022
1	Ketogenic Diet 01/2022
1	Mediterranean Diet 01/2022
1	Diet Therapy (Therapy, Diet) 01/2022